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NAD+

NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a prevalent electron transporter, coenzyme, and signaling molecule found in all cells of the body and is vital for cell function and viability.
NAD+ is essential for the metabolic processes and reactions that occur within our cells, as well as brain rejuvenation. All cellular events occurring within our bodies require the presence of NAD+.
Depletion of NAD+ has been associated with the onset of age related illness and disease, increased DNA damage, and mitochondrial dysfunction.
NAD+ is most commonly utilized by patients for its anti-aging benefits
that both increase cognitive function and prevent cognitive decline.
NAD+ Benefits
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Improved Cognitive Functions: Improved performance in mental clarity, focus, memory, and improved mood.
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Prevents Cognitive Decline and neurological cellular aging
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Protect against age related cognitive diseases like Alzheimer's and Parkinson's.
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Promote healing of GI disorders and improves overall digestive health
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Increased energy and metabolism
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Enhances Mitochondrial function and repairs Mitochondrial damage
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Improves hearing and eyesight function
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Improved cardiovascular health
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Addiction support: Decreases cravings and withdrawal symptoms
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Improved athletic performance and recovery from sports and exercise
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Improved sleep quality
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Anti-Aging Properties: Slows the overall aging process by supporting DNA repair and cellular signaling.
NAD+ risks and side effects
There are no current documented side effects or medication interactions.
NAD+ Administration
NAD+ dosing is 50mg administered two to three times weekly by IM injection. NAD+ is administered in a 3 month cycle.
NAD+ Peptide Combo Healing Therapies
Regenerative Combo (Muscle/ Joints / Cartilage repair)
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NAD+ and BPC 157: 12 week cycle
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NAD+, BPC 157, and AOD9604: 12 week cycle
Hormone Replacement Therapy
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NAD+ can be used in conjunction with HRT, TRT, Sermorelin HGH Peptide, and other Peptide Therapies
NAD+ 3 month Cognitive Enhancement Program
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NAD+ (3 month cycle)
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Mitocore supplement
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LENS Neurofeedback (1 session weekly)
**Semax and can be added to program

Research and References
1. Katsyuba, E., Romani, M., Hofer, D. et al. NAD+ homeostasis in health and disease. Nat Metab 2, 9–31 (2020). https://doi.org/10.1038/s42255-019-0161-5
2. Melanie R. McReynolds, Karthikeyani Chellappa, Joseph A. Baur. Age-related NAD+. Experimental Gerontology Volume 134, June 2020, 110888
3. Covarrubias, A.J., Perrone, R., Grozio, A. et al. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol 22, 119–141 (2021). https://doi.org/10.1038/s41580-020-00313-x
4. Hassina Massudi, Ross Grant, Gilles J Guillemin & Nady Braidy (2012) NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns, Redox Report, 17:1, 28-46, DOI: 10.1179/1351000212Y.0000000001
5. Peter Belenky, Katrina L. Bogan, Charles Brenner. NAD+ metabolism in health and disease
Trends in Biochemical Sciences. Volume 32, Issue 1, January 2007, Pages 12-19
6. Sara Amjad, Sabah Nisar, Ajaz A. Bhat, Ab Rauf Shah, Michael P. Frenneaux, Khalid Fakhro, Mohammad Haris , Ravinder Reddy, Zoltan Patay, Joseph Baur 10, Puneet Bagga. Role of NAD+ in regulating cellular and metabolic signaling pathways. Molecular Metabolism Volume 49, July 2021, 101195.
7. Xie, N., Zhang, L., Gao, W. et al. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Sig Transduct Target Ther 5, 227 (2020). https://doi.org/10.1038/s41392-020-00311-7.
8. NAD+ in aging, metabolism, and neurodegeneration. Eric Verdin. SCIENCE. 4 Dec 2015. Vol 350, Issue 6265 pp. 1208-1213.
9. Riekelt H. Houtkooper, Carles Cantó, Ronald J. Wanders, Johan Auwerx, The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways, Endocrine Reviews, Volume 31, Issue 2, 1 April 2010, Pages 194–223, https://doi.org/10.1210/er.2009-0026
10. Goody, M.F., Henry, C.A. A need for NAD+ in muscle development, homeostasis, and aging. Skeletal Muscle 8, 9 (2018). https://doi.org/10.1186/s13395-018-0154-1
11. Imai, Si., Guarente, L. It takes two to tango: NAD+ and sirtuins in aging/longevity control. npj Aging Mech Dis 2, 16017 (2016). https://doi.org/10.1038/npjamd.2016.17